生物技术进展 ›› 2024, Vol. 14 ›› Issue (5): 712-723.DOI: 10.19586/j.2095-2341.2024.0112

• 进展评述 • 上一篇    

农业基因编辑产品检测动态及发展趋势

王晶(), 关海涛, 张晓磊, 王堡槐, 刘宝海(), 温洪涛()   

  1. 黑龙江省农业科学院农产品质量安全研究所,农业农村部谷物及制品质量检验测试中心(哈尔滨),国家市场监督管理总局重点实验室(谷物及制品质量与安全),哈尔滨 150086
  • 收稿日期:2024-06-11 接受日期:2024-08-01 出版日期:2024-09-25 发布日期:2024-10-22
  • 通讯作者: 刘宝海,温洪涛
  • 作者简介:王晶E-mail: buyijingjing@163.com
  • 基金资助:
    科技创新2030-重大项目子课题(2022ZD040190803);黑龙江省农业科技创新跨越工程农业科技基础创新优青项目(CX22YQ08);黑龙江省自然科学基金优秀青年项目(YQ2022C032);黑龙江省省属科研院所科研业务费青年项目(CZKYF2024-1-C001);国家市场监督管理总局重点实验室(谷物及制品质量与安全)开放课题资助项目

Detection Dynamic and Development Tendency of Agricultural Gene Editing Products

Jing WANG(), Haitao GUAN, Xiaolei ZHANG, Baohuai WANG, Baohai LIU(), Hongtao WEN()   

  1. Quality and Safety Institute of Agricultural Products,Heilongjiang Academy of Agricultural Sciences,Quality Testing Center of Cereals and Their Products (Harbin),Ministry of Agriculture and Rural Affairs,Key Laboratory of Quality and Safety of Cereals and Their Products,State Administration for Market Regulation,Harbin 150086,China
  • Received:2024-06-11 Accepted:2024-08-01 Online:2024-09-25 Published:2024-10-22
  • Contact: Baohai LIU,Hongtao WEN

摘要:

基因编辑技术是重要的生物育种技术之一。随着生物育种产业化的高速发展,农业基因编辑产品呈现快速增长态势,然而其标识溯源检测技术的研发速度难以匹配知识产权保护和安全监管的需求,严重制约了产业的发展,亟需研发与现行检测体系相适应的基因编辑产品检测技术与方法。从主要的基因编辑系统和技术优势、靶点编辑类型着手,分析了不同类型基因编辑产品检测技术的特征和优缺点,提出了检测技术创新、检测与评价技术融合、监管技术体系细化三方面建议,以期为农业基因编辑产品标识、溯源技术研究提供参考,为完善我国农业生物技术产品监管体系提供技术支撑。

关键词: 基因编辑, CRISPR/Cas技术, 生物育种, 基因编辑产品检测技术

Abstract:

Gene editing technology is one of the essential biological breeding technologies. With the rapid development of biological breeding industrialization, agricultural gene editing products have shown a rapid growth trend. However, the speed of development of its identification and traceability detection technology cannot correspond to intellectual property protection and regulatory requirements. This seriously restricts the development of the industry. In this paper, we focused on the main gene editing systems, the technology advantages of various gene editing systems, and target editing types. Moreover, we analyzed the characteristics, advantages, and disadvantages of detection technology for gene editing products. Furthermore, three suggestions, innovation of detection technology, integration of detection and evaluation technology, and supervision technology system refinement, were proposed to provide reference for the research on the identification, traceability technology of agricultural gene editing products and technical support for improving the supervision system of agricultural biotechnology products.

Key words: gene editing, CRISPR/Cas technology, biological breeding, gene editing detection technology

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