关键词: 氢分子, 癌症, 氧化应激, 抗氧化, 抗炎症

Abstract: As a novel antioxidant, molecular hydrogen exhibits great efficacy in various diseases caused by oxidative stress and inflammatory. With a complex pathogenesis, cancer is difficult to prevent and cure. Numbers of malignancies are associated with chronic inflammation and oxidative stress. Therefore, molecular hydrogen may play a potential role in carcinogenesis and cancer therapy. Previous studies showed that molecular hydrogen may have the preventive and therapeutic effect in various tumors, as well as the synergistic effect in the tumor radiotherapy and chemotherapy with a decreasing side-effect. This paper reviewed the recent progress of molecular hydrogen in cancer prevention and treatment, and prospected the research direction  in the future, which was expected to provide reference for hydrogen application in cancer prevention and treatment.

Key words: molecular hydrogen, cancer, oxidative stress, antioxidant, anti-inflammatory