氢分子在皮肤疾病治疗中的潜力与前景

doi:10.19586/j.2095-2341.2023.0087

生物技术进展 ›› 2023, Vol. 13 ›› Issue (6): 875-881.DOI: 10.19586/j.2095-2341.2023.0087

• 进展评述 • 上一篇

氢分子在皮肤疾病治疗中的潜力与前景

杨建鸿¹(), 陈军¹, 李雪飞¹, 刘利君¹, 陈丽莉¹, 段昕所¹, 秦树存², 何磊¹()

^1.承德医学院附属医院皮肤病与性病科，河北承德 067000
^2.山东第一医科大学动脉粥样硬化研究所，山东泰安 271000

收稿日期:2023-06-24 接受日期:2023-09-21 出版日期:2023-11-25 发布日期:2023-12-12
通讯作者: 何磊
作者简介:杨建鸿 E-mail: 819587855@qq.com；
基金资助:
河北省财政厅卫健委政府资助临床医学优秀人才培养项目(ZF2023253);承德市科技计划自筹经费项目(202204A069)

The Potential and Prospect of Molecular Hydrogen in the Treatment of Skin Diseases

Jianhong YANG¹(), Jun CHEN¹, Xuefei LI¹, Lijun LIU¹, Lili CHEN¹, Xinsuo DUAN¹, Shucun QIN², Lei HE¹()

^1.Department of Dermatology and Venereology，Affiliated Hospital of Chengde Medical University，Hebei Chengde 067000，China
^2.Institute of Atherosclerosis，Shandong First Medical University，Shandong Taian 271000，China

Received:2023-06-24 Accepted:2023-09-21 Online:2023-11-25 Published:2023-12-12
Contact: Lei HE

摘要/Abstract

摘要：

皮肤是人体最大的器官，其在防护环境中的物理、化学和生物危害方面发挥着关键作用。然而，当这些危害超出防御系统的抗氧化能力时，则可能导致体内氧化应激和慢性炎症的发生，并进一步损坏胶原纤维妨碍皮肤细胞功能，引起各种皮肤疾病。氢分子在医学领域具有广泛的应用前景，包括在皮肤疾病治疗领域。综述了氢分子对皮肤病的抗氧化、抗炎作用机制及给药方式，总结了氢分子在不同类型皮肤病及美容护肤方面的应用进展，并讨论了氢分子用于皮肤病治疗的安全性。氢分子有望成为预防和治疗皮肤相关疾病的有效方法。

关键词: 氢分子, 皮肤疾病, 氧化应激, 美容

Abstract:

The skin， as the largest organ of the human body， plays a crucial role in protecting against physical， chemical， and biological hazards from environment. However， when these hazards exceed the antioxidant capacity of the defense system， it can lead to oxidative stress and chronic inflammation in the body， further damaging collagen fibers and hindering the function of skin cells， resulting in various skin diseases. Molecular hydrogen （H₂） has broad prospects for application in the medical field， including the treatment of skin diseases. This review summarized the antioxidant and anti-inflammatory mechanisms of molecular hydrogen in skin diseases and its administration methods. It also provided an overview of the progress in the application of molecular hydrogen in different types of skin diseases and cosmetic skincare， as well as discussing the safety of molecular hydrogen for the treatment of skin diseases. Molecular hydrogen is expected to be an effective approach for the prevention and treatment of skin-related diseases.

Key words: molecular hydrogen, skin diseases, oxidative stress, beauty

中图分类号:

Q505

杨建鸿, 陈军, 李雪飞, 刘利君, 陈丽莉, 段昕所, 秦树存, 何磊. 氢分子在皮肤疾病治疗中的潜力与前景[J]. 生物技术进展, 2023, 13(6): 875-881.

Jianhong YANG, Jun CHEN, Xuefei LI, Lijun LIU, Lili CHEN, Xinsuo DUAN, Shucun QIN, Lei HE. The Potential and Prospect of Molecular Hydrogen in the Treatment of Skin Diseases[J]. Current Biotechnology, 2023, 13(6): 875-881.

图/表 1

参考文献 29

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氢分子在皮肤疾病治疗中的潜力与前景

The Potential and Prospect of Molecular Hydrogen in the Treatment of Skin Diseases

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