关键词: 硒, 健康效应, 流行病学, 人群研究

Abstract: Selenium (Se) is one of the essential trace elements in human body. The environmental background value of Se is extremely uneven, both Se deficient areas and Se rich areas exist. In the past 10 years, a large number of epidemiology studies investigated the association between Se and mortality, cancer, cardiovascular disease, type 2 diabetes mellitus, and reproduction. Based on the recent population studies, this paper comprehensively expounded the current research progress on Se and diseases above, and discussed the relationship between Se and disease from an epidemiological perspective.

Key words: selenium, health effect, epidemiology, population-based study