氢气与肠道菌群的关系研究进展

doi:10.19586/j.2095-2341.2022.0060

生物技术进展 ›› 2022, Vol. 12 ›› Issue (6): 847-852.DOI: 10.19586/j.2095-2341.2022.0060

氢气与肠道菌群的关系研究进展

刘梓嘉(), 姜雪, 仪杨, 王濛, 马晨, 宋怡菲, 谢飞()

北京工业大学环境与生命学部，北京 100124

收稿日期:2022-04-21 接受日期:2022-05-05 出版日期:2022-11-25 发布日期:2022-11-30
通讯作者: 谢飞
作者简介:刘梓嘉 E-mail: 18852864492@163.com；
基金资助:
军委后勤保障部开放研究重点项目(BHJ17L018)

Research Progress on the Relationship Between Hydrogen and Intestinal Flora

Zijia LIU(), Xue JIANG, Yang YI, Meng WANG, Cheng MA, Yifei SONG, Fei XIE()

Faculty of Environment and Life，Beijing University of Technology，Beijing 100124，China

Received:2022-04-21 Accepted:2022-05-05 Online:2022-11-25 Published:2022-11-30
Contact: Fei XIE

摘要/Abstract

摘要：

目前，氢气已被证实在多种疾病中具有显著的医学效应，然而其发挥效应的分子机制并不清楚。肠道菌群被人们看作人体的一个重要“器官”，与人类健康的关系密不可分。研究表明，人类肠道菌群中存在着大量能够进行氢气代谢的菌群，这些菌群的变化可能与多种疾病的发生发展密切相关。此外，研究还发现外源氢气干预可能通过重塑肠道菌群改善炎症性肠病、脂肪性肝病等。综述了肠道菌群的氢气代谢及其与疾病发生发展的关系以及外源氢气干预通过调节肠道菌群影响疾病进展的相关研究，希望能为致力于从肠道菌群角度研究氢气医学效应的科研工作者提供帮助。

关键词: 氢气代谢, 肠道菌群, 氢化酶, 外源氢气干预, 疾病发生发展

Abstract:

Hydrogen has been proved to have significant medical effects on a variety of diseases， however， the molecular mechanism of its effect have not been fully elucidated. Intestinal flora has been regarded as an important "organ" of human body， which is closely related to human health. Studies have shown that there are a large number of bacteria capable of hydrogen metabolism in human intestinal flora， and the changes of these bacteria may be closely related to the occurrence and development of a variety of diseases. In addition， the study also found that exogenous hydrogen intervention may improve inflammatory bowel disease， fatty liver disease and other diseases through the remodeling of intestinal flora. This paper reviewed the hydrogen metabolism of intestinal microflora and its relationship with the occurrence and development of diseases， as well as the related research on the effect of exogenous hydrogen intervention on disease progression by regulating intestinal microflora， hoping to provide help for researchers who are committed to studying the medical effects of hydrogen from the perspective of intestinal flora.

Key words: hydrogen metabolism, intestinal flora, hydrogenase, exogenous hydrogen intervention, occurrence and development of diseases

中图分类号:

刘梓嘉, 姜雪, 仪杨, 王濛, 马晨, 宋怡菲, 谢飞. 氢气与肠道菌群的关系研究进展[J]. 生物技术进展, 2022, 12(6): 847-852.

Zijia LIU, Xue JIANG, Yang YI, Meng WANG, Cheng MA, Yifei SONG, Fei XIE. Research Progress on the Relationship Between Hydrogen and Intestinal Flora[J]. Current Biotechnology, 2022, 12(6): 847-852.

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氢气与肠道菌群的关系研究进展

Research Progress on the Relationship Between Hydrogen and Intestinal Flora

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