关键词: 畜禽粪便, 抗生素, 耐药基因, 归趋

Abstract: Antibiotics are widely used in animal husbandry due to their outstanding functions, including promoting animal growth, improving feed conversion efficiency, and preventing and treating animal diseases. However, only a small amount of antibiotics can be absorbed and degraded by animals, and most of the ingested veterinary antibiotics are excreted into the environment through feces and urine in the form of prototype or antibacterial metabolites. Apart from antibiotics, manure is also a reservoir of antibiotic resistance genes (ARGs) which contains numerous antibiotic resistant bacteria. Antibiotics and ARGs in the manure can transmit in the environment with the application of manure. Furthermore, residual antibiotics can further enrich ARGs in the environment. It has the potential harm to the human health and ecosystem. Based on this situation, environmental fate of antibiotics and ARGs in animal manure was summarized in order to provide a scientific reference for studying the harm of antibiotics and ARGs to ecosystem and human health.

Key words: animal manure, antibiotics, antibiotic resistance genes, fate