关键词: 壳寡糖, 免疫调节, 糖脂代谢紊乱, 医学, 农业生产

Abstract: Chitosan oligosaccharide (COS) is a low molecular weight polymer linked by 2~10 glucosamines via β-1,4 glycosidic linkages, which can be obtained by chemical or enzymatic degradation of chitin or chitosan. It has extensive research and application value in various fields such as medicine and agricultural production. COS is naturally non-toxic, low molecular weight, excellent water solubility, easy to absorb and has good biocompatibility. In addition, COS exhibits strong biological properties, including anti-tumor, anti-inflammation, immune-stimulation, anti-bacterial, improving glucose and lipid metabolism disorder, neuroprotection and so on. This paper summarized the preparation and characterization, biological function and application of COS, and discussed the existing problems and future research directions, in order to fully understand COS and provide reference for further research and development.

Key words: chitosan oligosaccharide, immunoregulation, glucose and lipid metabolism disorder, medicine, agricultural production