生物技术进展 ›› 2020, Vol. 10 ›› Issue (5): 479-486.DOI: 10.19586/j.2095-2341.2020.0046

• 进展评述 • 上一篇    下一篇

植物维生素E生物强化研究进展

姚兴兰,王磊*,张兰*   

  1. 中国农业科学院生物技术研究所, 北京 100081
  • 收稿日期:2020-04-17 出版日期:2020-09-25 发布日期:2020-08-05
  • 通讯作者: 王磊 E-mail:caaswlwl@163.com;张兰 E-mail:zhanglan20000@163.com
  • 作者简介:姚兴兰 E-mail:15751004149@163.com
  • 基金资助:
    国家转基因生物新品种培育科技重大专项(2016ZX08003-002;2018ZX0800303B)。

Progress of Vitamin E Biofortification in Plants

YAO Xinglan, WANG Lei, ZHANG Lan   

  1. Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China
  • Received:2020-04-17 Online:2020-09-25 Published:2020-08-05

摘要: 维生素E是一种只能在光合组织中合成的脂溶性小分子有机化合物,是人体和动物营养不可缺少的重要维生素。由于植物中维生素E含量较低,人类大多处于慢性缺乏维生素E——“隐性饥饿”的状态,而动物饲料中则需要添加外源合成的维生素E以满足其营养需求。因此,提高植物中维生素E的含量是改善维生素E缺乏的重要途径之一。从维生素E的合成途径入手,详细地综述了维生素E合成关键酶基因的表达变化以及前体物质的含量变化对维生素E合成的影响,发现三烯生育酚和α-生育酚的生物强化效果较好,而生育酚总量提高受限;进而从遗传的角度探讨了维生素E合成受限的原因以及遗传上可能影响维生素E合成的其他代谢途径;最后结合可能影响维生素E合成的调控因子以及其前体物质的转运等方面为今后维生素E的生物强化提出了新的思路。

关键词: 维生素E, 合成途径, 前体物质, 生物强化, 遗传

Abstract: Vitamin E is a kind of fat-soluble antioxidant and it is synthesized only by photosynthetic organisms. Vitamin E is an important and indispensable vitamin for human and livestock. Due to the low content of vitamin E in plants, most of people are in a state of chronic deficiency of vitamin E——“hidden hunger”. Synthetic vitamin E is supplemented in the feed for optimal animal growth. Therefore, increasing the content of vitamin E in plants is one of the important ways to improve vitamin E deficiency. Starting from the biosynthetic pathway of vitamin E, this paper summarized the influence of key enzymes expression and precursors content on vitamin E in detail, pointed out that the biofortification effect of tocotrienol and α-tocopherol was efficient, while the increase of tocopherol content was limited. Furthermore, the reasons for the limitation of vitamin E biosynthesis and other metabolic pathways that may affect vitamin E synthesis were discussed from the genetic point of view. Finally, a new idea was proposed for vitamin E biofortification in the future by combining with the regulatory factors that may affect the biosynthesis of vitamin E and the transport of its precursors.

Key words: vitamin E, biosynthetic pathway, precursor, biofortification, genetic