关键词: 狂犬病毒, 糖蛋白, 中和抗体, 作用机制

Abstract: Rabies is a fatal zoonosis caused by rabies virus (RV). Rabies virus glycoprotein (RVG), the unique viral protein exposed on the surface of viral envelope, can induce the production of rabies neutralizing antibodies. This review focuses on recent advances in rabies virus, the structure and function of glycoprotein, progress of neutralizing antibodies and their action mechanism, which can provide theoretical foundations and development strategies for further study of neutralizing antibodies.

Key words: rabies virus, glycoprotein, neutralizing antibody, mechanism