生物技术进展 ›› 2024, Vol. 14 ›› Issue (6): 886-891.DOI: 10.19586/j.2095-2341.2024.0145

• 食药用菌生物技术专题 • 上一篇    下一篇

合成生物学在食用菌新赛道中的展望

刘昱1(), 李甜2(), 魏勇军2, 汪滢1(), 邹根1()   

  1. 1.上海市农业科学院食用菌研究所,国家食用菌工程技术研究中心,农业农村部南方食用菌资源利用重点实验室,上海 201403
    2.郑州大学药学院,合成生物学实验室,郑州 450001
  • 收稿日期:2024-09-02 接受日期:2024-10-14 出版日期:2024-11-25 发布日期:2024-12-27
  • 通讯作者: 汪滢,邹根
  • 作者简介:刘昱 E-mail: 2519331578@qq.com
    李甜 E-mail: tianlizzu@163.com第一联系人:刘昱和李甜为共同第一作者。

The Prospect of Synthetic Biology in the New Track of Edible Fungi

Yu LIU1(), Tian LI2(), Yongjun WEI2, Ying WANG1(), Gen ZOU1()   

  1. 1.Key Laboratory of Edible Fungi Resources and Utilization (South),National Engineering Research Center of Edible Fungi,Institute of Edible Fungi,Shanghai Academy of Agricultural Sciences,Shanghai 201403,China
    2.Laboratory of Synthetic Biology,College of Pharmacy,Zhengzhou University,Zhengzhou 450001,China
  • Received:2024-09-02 Accepted:2024-10-14 Online:2024-11-25 Published:2024-12-27
  • Contact: Ying WANG,Gen ZOU

摘要:

近年来,通过科技创新与推广绿色有机种植技术等手段,食用菌的品质和附加值明显提升。但是,同质化严重的问题也导致食用菌产业面临升级和结构调整等现实问题。同时,随着社会经济的发展,“低碳”“绿色”“循环”等发展新理念对产业提出了更高的要求。概述了食用菌合成生物学的研究进展及其在该领域的创新应用,希望能够将这一快速发展的领域纳入我国及其他国家的食用菌技术变革的新赛道中。重点讨论了以食用菌为基础的循环经济、人类健康和药学、替代蛋白、替代皮革、污染治理以及航空航天等应用领域发展的难点,并提出了利用合成生物学解决这些问题的应对措施。希望未来使用食用菌合成生物学可以更好地推动可持续的社会经济和生态发展。

关键词: 食用菌, 合成生物学, 可持续发展, 循环经济, 菌丝体皮革, 菌丝体蛋白

Abstract:

In recent years, the quality and added value of edible fungi have been significantly improved through the cutting-edge technological innovation. However, a challenge of homogenization has also led to practical problems such as upgrading and structural adjustment of the edible fungus industry. The development of social economy has put forward higher requirements for the industry to better respond to new development concepts including “low carbon”“green” and “recycling”. In this review, we summarized the research progress and innovative applications of mushroom-based synthetic biology, hoping to incorporate this rapidly developing field into the new track of fungal biotechnology change in China and other countries. It also focused on the difficulties in the development of mushroom-based circular economy, human health and pharmacy, alternative proteins, alternative leather, pollution control, and aerospace, and proposes countermeasures to solve these problems using synthetic biology. It is hoped that in the future, the mushroom-based synthetic biology can better promote sustainable socio-economic and ecological development.

Key words: edible fungi, synthetic biology, sustainable development, circular economy, mycelium leather, mycelium proteins

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