生物技术进展 ›› 2017, Vol. 7 ›› Issue (4): 290-295.DOI: 10.19586/j.2095-2341.2017.0024

• 综述 • 上一篇    下一篇

胶原蛋白肽金属螯合物及其生产制备工艺的研究进展

孙姗姗1,2,高亚辉1,陈俊德2*   

  1. 1.厦门大学生命科学学院, 福建 厦门 361005;
    2.国家海洋局第三海洋研究所, 国家海洋局海洋生物资源综合利用工程技术研究中心, 福建 厦门 361005
  • 收稿日期:2017-04-07 出版日期:2017-07-25 发布日期:2017-05-18
  • 通讯作者: 陈俊德,副研究员,主要从事蛋白工程研究。E-mail:jdchen@tio.org.cn
  • 作者简介:孙姗姗,硕士研究生,主要从事蛋白工程研究。E-mail: shshsun123@163.com。
  • 基金资助:
    国家自然科学基金项目(41106149;41676129)资助。

Progress of Collagen Peptide Metal Chelates and Related Production Technologies#br#

SUN Shanshan, GAO Yahui, CHEN Junde   

  1. 1.School of Life Sciences, Xiamen University, Fujian Xiamen 361005, China;
    2.Marine Biological Resource Comprehensive Utilization Engineering Research Center of the State Oceanic Administration, the Third Institute of Oceanography of the State Oceanic Administration, Fujian Xiamen 361005, China
  • Received:2017-04-07 Online:2017-07-25 Published:2017-05-18

摘要: 胶原蛋白肽金属螯合物是胶原蛋白肽与金属离子通过配位共价结合或吸附结合方式形成的螯合物。该螯合物作为金属矿物元素补充剂,具有生物利用率高、安全性高、生物活性高等优点。综述了胶原蛋白肽金属螯合物的螯合机理、稳定性、吸收利用、功能活性和生产制备工艺并展望了其开发应用前景,以期为相关研究提供参考。

关键词: 胶原蛋白肽金属螯合物, 螯合机理, 生物活性, 生产制备工艺

Abstract: Collagen peptide metal chelates are formed by collagen peptides and metal ions through coordinate covalent bonding or adsorption binding. They have been considered as the potential approach to delivering metal mineral elements to consumers with many virtues, such as higher bioavailability, higher safety and higher bioactivity. Chelate mechanism, stability, absorption and utilization, functional activity and production technologies of collagen metal chelates were reviewed and the development prospect were also foreseen in this paper, which was expected to provide reference for related reasearches.

Key words: collagen peptide metal chelates, chelate mechanism, functional activity, production technologies