关键词: 牛乳铁蛋白肽, 抗菌肽, 基因工程

Abstract: Lactoferricin bovine(LfcinB) is a kind of small peptide which derives from lactoferrin when it was mainly generated by the pepsin-mediated digestion from N-terminal of lactoferrin. It contains 25 amino acids residues and a number of biological functions, including antimicrobial, anticancer, antioxidant and immunomodulatory effects. So LfcinB has become the focus of research. To date, high process production costs made it  difficult to produce on more commercial level scale. Genetic engineering will be the best method to produce LfcinB. This paper gave an overview on antimicrobial activities of LfcinB and its production by genetic engineering including the advantage and improve, which aimed to provide new ideas about genetic engineering produce LfcinB.

Key words: lactoferricin bovine, antibacterial peptides, genetic engineering