生物技术进展 ›› 2013, Vol. 3 ›› Issue (2): 90-95.DOI: 10.3969/j.issn.2095-2341.2013.02.03

• 进展评述 • 上一篇    下一篇

超强辐射抗性微生物:耐辐射异常球菌

王金辉,周正富,张维,林敏,陈明*   

  1. 中国农业科学院生物技术研究所, 北京 100081
  • 收稿日期:2013-03-11 出版日期:2013-03-25 发布日期:2013-03-20
  • 通讯作者: 陈明,研究员,主要从事环境微生物的分子生物学研究。E-mail:chenmingbio@hotmail.com
  • 作者简介:王金辉,博士研究生,研究方向抗逆微生物分子生物学。
  • 基金资助:

    国家转基因新品种培育重大专项(2011ZX08009-003);农业部公益性行业科研专项(201103007);国家自然科学基金项目(31170081)资助。

Extremely Radiation-resistant Bacterium Deinococcus radiodurans

 WANG Jin-hui, ZHOU Zheng-fu, ZHANG Wei, LIN Min, CHEN Ming   

  1. Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China
  • Received:2013-03-11 Online:2013-03-25 Published:2013-03-20

摘要: 耐辐射异常球菌是革兰氏阳性菌,具有独特的细胞结构特征。基因组由两条染色体和两个质粒构成,GC含量较高。与异常球菌属的其他菌种不同,耐辐射异常球菌在整个指数生长期细胞都处于感受态,易于遗传操作。由于具有独特的细胞结构和超强的修复系统,耐辐射异常球菌具有超强电离辐射抗性、UV抗性、氧化抗性、干旱抗性等特征,极具研究和应用价值。

关键词: 耐辐射异常球菌, 电离辐射抗性, UV抗性, 氧化抗性, 干旱抗性

Abstract: Deinococcus radiodurans is Gram positive bacterium, possessing special cell structure. The genome comprises two chromosomes and two plastids, and the GC content is relatively high. Distincting from other Deinococcus bacteria, D. radiodurans is amenable to genetic manipulation owing to its natural transformability and the cells are competent throughout the exponential growth stage. Duing to unique structure and strong repair systems, D. radiodurans has strong ionizing radiation resistance, UV resistance, oxidation resistance, drought resistance and other characteristics, having great research and application value.

Key words: Deinococcus radiodurans, ionizing radiation resistance, UV resistance, oxidation resistance, drought resistance