基于专利数据分析热熔挤出技术在生物医药领域的应用

doi:10.19586/j.2095-2341.2023.0148

生物技术进展 ›› 2024, Vol. 14 ›› Issue (2): 331-337.DOI: 10.19586/j.2095-2341.2023.0148

• 研究论文 • 上一篇

基于专利数据分析热熔挤出技术在生物医药领域的应用

师帅¹(), 赵迎春²(), 林瑞红¹, 李文刚¹, 王烁¹, 于婧¹

^1.沈阳市知识产权保护中心，沈阳 110000
^2.沈阳市食品药品检验所，沈阳 110011

收稿日期:2023-11-14 接受日期:2024-02-02 出版日期:2024-03-25 发布日期:2024-04-17
作者简介:师帅 E-mail: shi1403@163.com
赵迎春 E-mail: 1687669275@qq.com第一联系人：（师帅、赵迎春并列第一作者）
基金资助:
辽宁省专利转化专项计划项目(2023-04-02)

Application of Hot Melt Extrusion Technology in Biomedicine Field Based on Patent Data

Shuai SHI¹(), Yingchun ZHAO²(), Ruihong LIN¹, Wengang LI¹, Shuo WANG¹, Jing YU¹

^1.Shenyang Intellectual Property Protection Center，Shenyang 110000，China
^2.Shenyang Food and Drug Control Institute，Shenyang 110011，China

Received:2023-11-14 Accepted:2024-02-02 Online:2024-03-25 Published:2024-04-17

摘要/Abstract

摘要：

热熔挤出技术是指将药物、增塑剂和聚合物等辅料在熔融状态下混合后，以一定的压力、速度和形状挤出形成药物产品的技术，对于改善并提高药物溶解度、改进制备缓控制剂方法具有重要意义。以生物医药产业领域的热熔挤出专利为分析样本，采用专利数据库数据及“定量+定性”分析方法，从专利产出趋势、主要竞争力量、热点技术等方面分析热熔挤出技术在生物医药产业领域中的应用，以期为该领域的研究决策提供参考。

关键词: 专利数据, 热熔挤出技术, 生物医药

Abstract:

Hot melt extrusion technology refers to the technology that drugs， plasticizers and polymers are mixed in the molten state and extruded to form drug products at a certain pressure， speed and shape， which is of great significance for improving and increasing the solubility of drugs and improving the preparation method of slow control agents. This paper took hot melt extrusion patents in pharmaceutical industry as analysis samples， adopted patent database data and qualitative analysis method to analyze the application of hot melt extrusion technology in pharmaceutical industry from the aspects of patent output trend， main competitive forces， hot technologies， etc.， so as to provide reference for research decision-making in this field.

Key words: patent data, hot melt extrusion technology, biomedicine

中图分类号:

Q819

师帅, 赵迎春, 林瑞红, 李文刚, 王烁, 于婧. 基于专利数据分析热熔挤出技术在生物医药领域的应用[J]. 生物技术进展, 2024, 14(2): 331-337.

Shuai SHI, Yingchun ZHAO, Ruihong LIN, Wengang LI, Shuo WANG, Jing YU. Application of Hot Melt Extrusion Technology in Biomedicine Field Based on Patent Data[J]. Current Biotechnology, 2024, 14(2): 331-337.

图/表 6

图1 全球热熔挤出技术专利历年申请趋势图

Fig. 1 Global patent application trend of hot melt extrusion technology over the years

图 2 全球热熔挤出技术专利来源国家或组织分析

Fig. 2 Contries or organizations analysis of the global patent sources for hot melt extrusion technology

图 3 全球热熔挤出技术专利技术构成

Fig. 3 Global patent composition of hot melt extrusion technology

图4 全球热熔挤出技术专利申请重要申请人

Fig. 4 Important applicants of global hot melt extrusion technology patent application

图 5 全球热熔挤出技术专利申请技术专利旭日图聚类算法

Fig. 5 Global hot melt extrusion technology patent application technology patent rising sun graph clustering algorithm

图6 中国热熔挤出技术专利申请技术被引用情况

Fig. 6 Citation of patent applications for hot melt extrusion technology in China

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基于专利数据分析热熔挤出技术在生物医药领域的应用

Application of Hot Melt Extrusion Technology in Biomedicine Field Based on Patent Data

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