关键词: 介孔二氧化硅纳米粒子, 恶性肿瘤诊疗, 纳米探针, 靶向给药系统, 药物可控释放

Abstract: Mesoporous silica nanoparticles have good application prospects in the field of biomedicine as novel nano-carriers. MSNs physical and chemical properties, which are different from traditional inorganic materials, play a key role in the diagnosis and therapy of malignant tumors. In particular, as the drug loading platforms with high loadings, good biocompatibility, targeting ability and the controllability for drug release, the mesoporous silica nanoparticles could be used to solve problems in the clinical diagnosis and therapy of malignant tumors. The application progress and development direction of the nanoprobe and targeted delivery system using MSNs was primarily discussed in order to provide ideas and references for the diagnosis and therapy of malignant tumors.

Key words: mesoporous silica nanoparticles, diagnosis and therapy of malignant tumors, nanoprobe, targeted delivery system , drug controlled release