关键词: 脂肪干细胞, 多向分化, 肌腱损伤修复, 组织工程, 种子细胞

Abstract: Adipose-derived stem cells (ADSCs) have more advantages than other tissue derived mesenchymal stem cells (MSCs), such as a wide range of sources, easy to acquire, amplification in vitro, as well as low immunogenicity, etc. More and more studies begin to pay close attention to how they can be applied to the treatment and regeneration of tissue damage. This paper reviewed the discovery and separation of ADSCs, and their differentiation ability towards tendon lineage, as well as the application in the aspect of tendon injuries both at home and abroad in recent years. The paper also analyzed the advantages and problems of ADSCs application. At last the future research direction was prospected.

Key words: dipose-derived stem cells, multilineage differentiation, tendon repair and regeneration, tissue engineering, seed cell