关键词: 乙酸盐, 腹腔注射, 食欲, 胰岛素分泌

Abstract: Acetic is produced from carbohydrates which are not digested by the intestinal microflora in the body. In mammals, acetic acid has been reported to increase the appetite of the host, improved glucose balance and insulin sensitivity. However, there are few studies on the mechanism of acetate in aquatic animals. In this experiment, zebrafish was used as the research object. Intraperitoneal injection of different concentrations of sodium acetate in zebrafish promoted the expression of orexigenic gene, but had no significant effect on the anorexigenic genes, indicating that sodium acetate can improve zebrafish appetite. On the other hand, the study found that intraperitoneal injection of sodium acetate promoted the expression of insulin secretion enhancement genes in the liver and intestine of zebrafish at 2 h, 4 h and 6 h post injection, indicating that sodium acetate has a positive effect on insulin secretion. Therefore, our research showed that sodium acetate can improve the appetite and promote the secretion of insulin in aquatic animals, expounded the mechanism of acetic acid on the growth of aquatic animals, and provided basis for the application of sodium acetate in production.

Key words: acetate, intraperitoneal injection, appetite, insulin secretion