关键词: 竞争排斥, 益生菌, 抗菌素抗性

Abstract: The concept of competitive exclusion (CE) was first proposed by Nurmi and Rantala in 1973. They described that introduction of gut contents originating from that adult birds can protect young birds against Salmonella infection. Then CE products were introduced in preventing and controling other pathogenic bacteria in gut. CE products have other functions, such as promoting growth, improving feed conversion ratio and decreasing mortality rates. Now, more than 20 kinds of CE products were developed and used in livestock and poultry raise in Europe and America. Although, the mechanism of this product is not clear now, some hypothesis have been proposed, such as competition of the attach site or nutrition, stimulation of the immunity response and generation of  kinds of anti-bacteria products. Because the popular of antibiotic resistance is becoming more serious, CE products will get a very wide application foreground.

Key words: competitive exclusion(CE), probiotics, antibiotic resistance